[Forschungsseminar-BSV] Forschungsseminar Computergrafik, Bildverarbeitung und Visualisierung

[Christian Heine]

E I N L A D U N G

S O N D E R T E R M I N

zum Forschungsseminar Computergrafik, Bildverarbeitung und 
Visualisierung am Mittwoch den 2009-01-14, 16:00 Uhr, Raum 1-43 in 
der Johannisgasse 26.


Wir hören einen Vortrag von

    Alexander Wiebel
    Universität Leipzig

mit dem Titel

    "Topological Flow Structures in a Mathematical
    Model for Rotation-Mediated Cell Aggregation"


Zum Inhalt:

In this talk we apply vector field topology methods to a 
mathematical model for the fluid dynamics of reaggregation 
processes in tissue engineering. The experimental background are 
dispersed embryonic retinal cells, which reaggregate in a rotation 
culture on a gyratory shaker, according to defined rotation and 
culture conditions. Under optimal conditions, finally complex 3D 
spheres result. In order to optimize high throughput drug testing 
systems of biological cell and tissue models, a major aim is to 
understand the role which the fluid dynamics play in this process. 
To allow for a mathematical analysis, an experimental model system 
was set up, using micro-beads instead of spheres within the culture 
dish. The qualitative behavior of this artificial model was 
monitored in time by using a camera. For this experimental setup a 
mathematical model for the bead-fluid dynamics was derived, 
analyzed and simulated. The simulations showed that the beads form 
distinctive clusters in a layer close to the bottom of the petri 
dish. To analyze these patterns further, we perform a topological 
analysis of the velocity field within this layer of the fluid. We 
find that traditional two-dimensional visualization techniques like 
path lines, streak lines and current time-dependent topology 
approaches are not able to answer the posed questions. We discuss 
the problems of these techniques and develop a new approach that 
measures the density of advected particles in the flow to find the 
moving point of particle aggregation. Using the density field the 
path of the moving aggregation point is extracted.

Der Vortrag wird in Deutsch gehalten.

Weitere Informationen zum Forschungsseminar sind auf der Webseite 
http://www.informatik.uni-leipzig.de/bsv/bsvneu/index.php?option=com_content&task=view&id=117&Itemid=111 
zu finden.

Alle Interessierten sind im Namen von Prof. Dr. Scheuermann herzlich 
eingeladen.

Mit freundlichen Grüßen,
Christian Heine